66898-62-2 Talniflumate AKSci M935
 
 
Loading Please Wait...
  M935    
Talniflumate
, 98% (HPLC)
 
Lomucin
Somalgen
Talniflumatum
more..




IDENTITY
CAS Number:66898-62-2
MDL Number:MFCD00866135
MF:C21H13F3N2O4
MW:414.33
SPECIFICATIONS & PROPERTIES
Purity:98% (HPLC)
Spectra:LCMS, FT-IR, HPLC
Physical Form:Pale yellow powder
Melting Point:165-170°C
Long-Term Storage:Store at room temperature

BIOLOGICAL INFO
Solubility:DMSO: 5 mg/mL clear (warmed)
Application(s):An inhibitor of Cox and Cl-/HCO3- exchange

REVIEW

 Talniflumate is an orally available, potent and selective inhibitor of core mucin-synthesizing enzyme GCNT3 (core 2 b-1,6 N-acetylglucosaminyltransferase). Talniflumate decreases GCNT3 expression and production of mucins in vivo and in vitro. Talniflumate improves responsiveness of pancreatic tumors to gefitinib. Talniflumate is a potent calcium-activated chloride channel (CaCC) blocker.

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of July 17, 2019


Download SDS

CATEGORIES

 APIs and Bioactives > NSAIDs


PubChem