56610-72-1 7-MAC AKSci L871
 
 
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  L871    AKSci Bulk Reagent
7-MAC, >95% (HPLC)
 
Diphenylmethyl (6R,7S)-7-Amino-7-methoxy-3-[(1-methyl-1H-tetrazol-5-yl)thiomethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
7-ACA-3-MTT-7-MO
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid
IDENTITY
CAS Number:56610-72-1
MDL Number:MFCD08704705
MF:C24H24N6O4S2
MW:524.62
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:>95% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:120-130°C
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Form:Free Base

REVIEW
 7-MAC (7-methoxyaminocephalosporin) is a key intermediate in the preparation of number of cephalopsporin antibacterials, for example, cefotetan, cefmetazole, cefaclor, cefbuperazone and cefminox.

REFERENCES
[1]Koppel, Gary A. 7beta-Acylamido-7alpha-methoxycephalosporins Ger. Offen. (1975), DE 2451931 A1 19750507.
[2] Iwamatsu, Katsuyoshi; Inouye, Shigeharu; Tsuruoka, Takashi; Mizutani, Kazuko; Omoto, Shoji; Ogino, Hiroko; Miyauchi, Keinosuke; Watanabe, Tadahiro; Niida, Taro Synthesis and biological activity of 7beta-[[(2-amino-2-carboxyethyl)thio]acetamido]-7alpha-methoxycephalosporin derivatives. Journal of Antibiotics (1983), 36(3), 229-41.
[3] Ohi, Nobuhiro; Aoki, Bunya; Shinozaki, Teizo; Moro, Kanzi; Kuroki, Toshio; Noto, Takao; Nehashi, Toshiyuki; Matsumoto, Masahiko; Okazaki, Hiroshi; Matsunaga, Isao Semisynthetic β-lactam antibiotics. IV. Synthesis and antibacterial activity of new ureidocephalosporin and ureidocephamycin derivatives containing a catechol moiety or its acetate. Chemical & Pharmaceutical Bulletin (1987), 35(5), 1903-9.
[4] Naito, Kenji; Morita, Tadashi; Kaneda, Soichi; A new process for the preparation of cefmetazole Jpn. Kokai Tokkyo Koho (1987), JP 62089689 A 19870424.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
None

Hazard Statements
None

Precautionary Statements
Notavailable

Current as of November 21, 2024


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CATEGORIES
 APIs and Bioactives > Antibacterials


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