79350-37-1 Cefixime AKSci K403
 
 
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  K403    AKSci Bulk Reagent
Cefixime
, 98% (HPLC)
 



IDENTITY
CAS Number:79350-37-1
MDL Number:MFCD00865020
MF:C16H15N5O7S2
MW:453.45
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:>300°C
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Application(s):Third generation cephalosporin antibiotic

REVIEW

 Like all beta-lactam antibiotics, cefixime binds to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, causing the inhibition of the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that cefixime interferes with an autolysin inhibitor.

REFERENCES
[1]McMillan A, Young H: The treatment of pharyngeal gonorrhoea with a single oral dose of cefixime. Int J STD AIDS. 2007 Apr;18(4):253-4.
[2] Adam D, Hostalek U, Troster K: 5-day cefixime therapy for bacterial pharyngitis and/or tonsillitis: comparison with 10-day penicillin V therapy. Cefixime Study Group. Infection. 1995;23 Suppl 2:S83-6.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Danger

Hazard Statements
H317; H334

Precautionary Statements
P261; P272; P280; P285; P302+P352; P304+P341; P321; P333+P313; P342+P311; P363; P501


Current as of October 15, 2024


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CATEGORIES

 APIs and Bioactives > Antibacterials, Cephalosporins


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