68-41-7 D-Cycloserine AKSci K138
 
 
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  K138    
D-Cycloserine
, 98% (HPLC)
 
(R)-4-Amino-3-isoxazolidone
4-Amino-3-isoxazolidinone




IDENTITY
CAS Number:68-41-7
MDL Number:MFCD00005353
MF:C3H6N2O2
MW:102.09
EINECS:200-688-4
BRN:80798
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98% (HPLC)
Spectra:NMR, LCMS, HPLC, FT-IRPolarimetry
Physical Form:White powder
Melting Point:140-146°C
Optical Rotation:+115.0±5.0° (c=2, H2O)
Long-Term Storage:Store long-term at 2-8°C
HAZARDOUS MATERIALS INFORMATION
Not hazardous material

BIOLOGICAL INFO
Application(s):Antibiotic

REVIEW

 Cycloserine is an analog of the amino acid D-alanine. It interferes with an early step in bacterial cell wall synthesis in the cytoplasm by competitive inhibition of two enzymes, L-alanine racemase, which forms D-alanine from L-alanine, and D-alanylalanine synthetase, which incorporates D-alanine into the pentapeptide necessary for peptidoglycan formation and bacterial cell wall synthesis.

GHS

Pictograms

Signal Word
None

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of June 20, 2021


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CATEGORIES

 Amino Acids > Serine
 APIs and Bioactives > Antibacterials
 APIs and Bioactives > Antibacterials


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