17440-83-4 Amiloride hydrochloride dihydrate AKSci J99713
 
 
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  J99713    AKSci Bulk Reagent
Amiloride hydrochloride dihydrate, 95%
 
MK-870
N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride hydrate
IDENTITY
CAS Number:17440-83-4
MDL Number:MFCD00211292
MF:C6H8ClN7O.HCl.2H2O
MW:302.12
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:95%
Physical Form (at 20°C):Solid
Melting Point:293.5°C
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
UN #:UN2811
Hazard Class:6.1; Poison
Packing Group:III
A hazmat fee may apply to certain package sizes and shipment methods. Please check pricing table for an indicator of applicable hazmat fees.

BIOLOGICAL INFO
Solubility:H2O: 50mg/mL
Application(s):Epithelial sodium channel blocker
Form:HCl salt

REVIEW
 Amiloride is a potassium-sparing diuretic that is used in the management of hypertension and congestive heart failure. Amiloride works by directly blocking the epithelial sodium channel (ENaC) thereby inhibiting sodium reabsorption in the late distal convoluted tubules, connecting tubules, and collecting ducts in the kidneys. This promotes the loss of sodium and water from the body, but without depleting potassium.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Danger

Hazard Statements
H301

Precautionary Statements
P264; P270; P301+P310; P321; P330; P405; P501

RELATED PRODUCTS
O373Amiloride hydrochloride dihydrate
U460Amiloride

Current as of January 28, 2025


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CATEGORIES
 APIs and Bioactives > Diuretics


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