908-54-3 Diminazene diaceturate AKSci J99623
 
 
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  J99623    
Diminazene diaceturate, 95%
 
Berenil
IDENTITY
CAS Number:908-54-3
MDL Number:MFCD00058386
MF:C22H29N9O6
MW:515.52
EINECS:212-999-2
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:95%
Physical Form (at 20°C):Solid
Melting Point:219-228°C
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:50mg/ml in H2O; clear yellow to orange solution
Application(s):DNA and RNA binder

REVIEW
 Diminazene diaceturate is a di-amidine also known as 4,4'-(1-Triazene-1,3- diaceturate is indicated for prophylactics and treatment of babesia, piroplasmosis and trypanosomiasis in camel, cattle, cats, dogs, goats, horse, sheep and swine. Trypanosomiasis or trypanosomosis is the name of several diseases in vertebrates caused by parasitic protozoan trypanosomes of the genus Trypanosoma. diyl)bis(benzenecarboximidamide). It binds DNA and RNA and is an antibacterial and antiprotozoal active against babesia, piroplasmosis and trypanosomiasis.

REFERENCES
[1]Zimmer C; Wahnert U; Nonintercalating DNA-binding ligands: specificity of the interaction and their use as tools in biophysical, biochemical and biological investigations of the genetic material. Progress in biophysics and molecular biology (1986), 47(1), 31-112.
[2] Dieleman EF; Trypanosomiasis in Indonesia. A review of research, 1900-1983. Vet Q. 1986 Jul;8(3):250-6.
[3] Thibault, J. M.; Jaussaud, P. Diminazene and its use in the dog. Note 1: Pharmacological and therapeutic aspects Revue de Medecine Veterinaire (Toulouse, France) (1987), 138(1), 45-9.
[4] Peregrine AS, Mamman M., Pharmacology of diminazene: a review. Acta Trop. 1993;54(3-4):185-203.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

RELATED PRODUCTS
K658Diminazene diaceturate

Current as of October 15, 2024


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CATEGORIES
 APIs and Bioactives > Antiparasitics


PubChem
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