51-60-5 Neostigmine methyl sulfate AKSci J99020
 
 
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  J99020    
Neostigmine methyl sulfate, 95%
 
3-(N,N-Dimethylcarbamoyloxy)-N,N,N,-trimethylanilinium methyl sulfate
(3-Hydroxyphenyl)trimethylammonium Methyl Sulfate Dimethylcarbamate
IDENTITY
CAS Number:51-60-5
MDL Number:MFCD00011796
MF:C13H22N2O6S
MW:334.39
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:95%
Physical Form (at 20°C):Solid
Melting Point:146-148°C
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
UN #:UN2811
Hazard Class:6.1; Poison
Packing Group:II
A hazmat fee may apply to certain package sizes. Please check pricing table for an indicator of applicable hazmat fees.

BIOLOGICAL INFO
Application(s):Cholinesterase inhibitor

REVIEW
 Neostigmine is a parasympathomimetic, specifically, a reversible cholinesterase inhibitor. The drug inhibits acetylcholinesterase which is responsible for the degredation of acetylcholine. So, with acetylcholinesterase inhibited, more acetylcholine is present By interfering with the breakdown of acetylcholine, neostigmine indirectly stimulates both nicotinic and muscarinic receptors which are involved in muscle contraction.. It does not cross the blood-brain barrier.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Danger

Hazard Statements
H300; H315; H319; H334; H335

Precautionary Statements
P261; P264; P270; P271; P280; P285; P301+P310; P302+P352; P304+P340; P305+P351+P338; P321; P330; P332+P313; P337+P313; P342+P311; P362; P403+P233; P405; P501

Current as of April 16, 2024


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CATEGORIES
 APIs and Bioactives > AChR Agonists


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