70359-46-5 Brimonidine tartrate AKSci J98894
 
 
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  J98894    
Brimonidine tartrate, 95%
 



IDENTITY
CAS Number:70359-46-5
MDL Number:MFCD07773072
MF:C11H10BrN5.C4H6O6
MW:442.22
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:95%
Physical Form (at 20°C):Light yellow powder
Melting Point:213-218°C
Long-Term Storage:Store long-term at -20°C
DOT/IATA TRANSPORT INFORMATION
UN #:UN2811
Hazard Class:6.1; Poison
Packing Group:III
A hazmat fee may apply, depending on the amount ordered.

BIOLOGICAL INFO
Solubility:Soluble in DMSO and Methanol

REVIEW
 Brimonidine is an alpha adrenergic receptor agonist (primarily alpha-2). It has a peak ocular hypotensive effect occurring at two hours post-dosing. Fluorophotometric studies in animals and humans suggest that Brimonidine has a dual mechanism of action by reducing aqueous humor production and increasing uveoscleral outflow.

REFERENCES
[1]Toris, C.; Camras, C.; Yablonski, M. (1999). Acute versus chronic effects of brimonidine on aqueous humor dynamics in ocular hypertensive patients. American journal of ophthalmology 128 (1): 8-14. PMID 10482088.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of January 25, 2022


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CATEGORIES
 APIs and Bioactives > Adrenergic Agonists


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