70359-46-5 Brimonidine tartrate AKSci J98894
 
 
Loading Please Wait...
  J98894    
Brimonidine tartrate
, 95%
 



IDENTITY
CAS Number:70359-46-5
MDL Number:MFCD07773072
MF:C11H10BrN5.C4H6O6
MW:442.22
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:95%
Physical Form (at 20°C):Solid
Melting Point:213-218°C
Long-Term Storage:Store long-term at -20°C
DOT/IATA TRANSPORT INFORMATION
UN #:UN2811
Hazard Class:6.1; Poison
Packing Group:III
A hazmat fee may apply, depending on the amount ordered.

BIOLOGICAL INFO
Solubility:Soluble in DMSO and Methanol

REVIEW

 Brimonidine is an alpha adrenergic receptor agonist (primarily alpha-2). It has a peak ocular hypotensive effect occurring at two hours post-dosing. Fluorophotometric studies in animals and humans suggest that Brimonidine has a dual mechanism of action by reducing aqueous humor production and increasing uveoscleral outflow.

REFERENCES
[1]Toris, C.; Camras, C.; Yablonski, M. (1999). Acute versus chronic effects of brimonidine on aqueous humor dynamics in ocular hypertensive patients. American journal of ophthalmology 128 (1): 8-14. PMID 10482088.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of October 1, 2022


Download SDS Request COA

⚠️
These chemical products are for research and development use only. They are not for diagnostic, therapeutic, cosmetic, or human and animal uses. They are not sold to individuals. Additional restrictions may apply.
New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information.


CATEGORIES

 APIs and Bioactives > Adrenergic Agonists


PubChem