154992-24-2 RU58841 AKSci J96212
 
 
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  J96212    
RU58841
, 95%
 
4-[3-(4-Hydroxybutyl)-4,4-dimethyl-2,5-dioxo-1-imidazolidinyl]-2-(trifluoromethyl)benzonitrile




IDENTITY
CAS Number:154992-24-2
MDL Number:MFCD00925776
MF:C17H18F3N3O3
MW:369.34
SPECIFICATIONS & PROPERTIES
Purity:95%
Physical Form:White powder
Density:1.4
Refractive Index:1.56
Long-Term Storage:Store at room temperature

BIOLOGICAL INFO
Solubility:DMSO

REVIEW

 A specific androgen receptor antagonist or anti-androgen; RU 58841 has a dramatic effect on hair regrowth.

REFERENCES
[1]Blaschke T, Kankate L, Kramer KD.Structure and dynamics of drug-carrier systems as studied by parelectric spectroscopy.Adv Drug Deliv Rev. 2007 Jul 10;59(6):403-10. Epub 2007 May 3.
[2] Battmann T, Bonfils A, Branche C, Humbert J, Goubet F, Teutsch G, Philibert D.RU 58841, a new specific topical antiandrogen: a candidate of choice for the treatment of acne, androgenetic alopecia and hirsutism.J Steroid Biochem Mol Biol. 1994 Jan;48(1):55-60.
[3] Matias JR, Gaillard M.Local inhibition of sebaceous gland growth by topically applied RU 58841.Ann N Y Acad Sci. 1995 Jun 12;761:56-65.
[4] Münster U, Nakamura C, Haberland A, Jores K, Mehnert W, Rummel S, Schaller M, Korting HC, Zouboulis ChC, Blume-Peytavi U, Schäfer-Korting M.RU 58841-myristate--prodrug development for topical treatment of acne and androgenetic alopecia.Pharmazie. 2005 Jan;60(1):8-12.

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of July 6, 2020


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CATEGORIES

 APIs and Bioactives > Antiandrogens


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