104239-97-6 4-Aza-5alpha-androstan-1-ene-3-one-17beta-carboxylic acid AKSci J96084
 
 
Loading Please Wait...
  J96084    
4-Aza-5alpha-androstan-1-ene-3-one-17beta-carboxylic acid, 95%
 
3-Oxo-4-aza-5α-androst-1-ene-17-carboxylic acid
IDENTITY
CAS Number:104239-97-6
MDL Number:MFCD08063794
MF:C19H27NO3
MW:317.43
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:95%
Physical Form (at 20°C):Solid
Melting Point:>250°C
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

REVIEW
 4-Aza-5alpha-androstan-1-ene-3-one-17beta-carboxylic acid or Dutasteride (trademark name Avodart, manufactured by GlaxoSmithKline) is a dual (type 1 and 2) 5-alpha reductase inhibitor that inhibits conversion of testosterone to dihydrotestosterone (DHT). It is used for benign prostatic hyperplasia and its chemopreventation, however increases the risk of erectile dysfunction and decrease sexual desire.

REFERENCES
[1]Zhao, Shuang; Bioorganic & Medicinal Chemistry Letters 2011, V21(11), P3439-3442
[2] Satyanarayana, Komati; Organic Process Research & Development 2007, V11(5), P842-845
[3] Zhang, Kui-Ping; Journal of Chinese Pharmaceutical Sciences 2007, V16(3), P233-235
[4] Rasmusson, Gary H.; Reynolds, Glenn F.; Steinberg, Nathan G.; Walton, Edward; Patel, Gool F.; Liang, Tehming; Cascieri, Margaret A.; Cheung, Anne H.; Brooks, Jerry R.; Berman, Charles; Azasteroids: structure-activity relationships for inhibition of 5alpha-reductase and of androgen receptor binding. Journal of Medicinal Chemistry (1986), 29(11), 2298-315.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of May 22, 2025


Download SDS Request COA

All products are stocked and shipped from the SF Bay, California, USA via FedEx, UPS or DHL.
All batches backed with full quality assurance.
⚠️
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.


CATEGORIES
 APIs and Bioactives > Antiandrogens, Steroid Hormones


PubChem
  @PubMed