180200-66-2 Gatifloxacine sesquihydrate AKSci J95486
 
 
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  J95486    AKSci Bulk Reagent
Gatifloxacine sesquihydrate, 95%
 
(+-)-1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid, sesquihydrate
IDENTITY
CAS Number:180200-66-2
MDL Number:MFCD22373645
MF:C19H22FN3O4·1.5(H2O)
MW:402.01 (384.47 anhy)
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:95%
Physical Form (at 20°C):Solid
Melting Point:185-188°C
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Application(s):Antibiotic; Bacterial enzymes DNA gyrase and topoisomerase IV inhibitor
Form:Hydrate

REVIEW
 An antibiotic of the fourth-generation fluoroquinolone family. The drug inhibits the bacterial enzymes DNA gyrase and topoisomerase IV.

REFERENCES
[1]Malik M, Chavda K, Zhao X, Shah N, Hussain S, Kurepina N, Kreiswirth BN, Kerns RJ, Drlica K (2012). Induction of mycobacterial resistance to quinolone class antimicrobials. Antimicrob Agents Chemother. 56(7):3879-87. PMID 22564842.
[2] Juárez-Verdayes MA, Parra-Ortega B, Hernández-Rodríguez C, Betanzos-Cabrera G, Rodríguez-Martínez S, Cancino-Diaz ME, Cancino-Diaz JC (2012). Identification and expression of nor efflux family genes in Staphylococcus epidermidis that act against gatifloxacin. Microb Pathog. 52(6):318-25. PMID 22426170.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H302; H312; H332

Precautionary Statements
P261; P264; P270; P271; P280; P301+P312; P302+P352; P304+P340; P312; P322; P330; P363; P501

RELATED PRODUCTS
X5018Gatifloxacin mesylate
F432Gatifloxacine sesquihydrate
O378Gatifloxacin hydrochloride

Current as of October 16, 2024


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All products are stocked and shipped from the SF Bay, California, USA via FedEx, UPS or DHL.
All batches backed with full quality assurance.
⚠️
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.


CATEGORIES
 APIs and Bioactives > Antibacterials, Quinolones


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