479-18-5, 52756-53-3; 68350-70-9 7-(2,3-Dihydroxypropyl)theophylline AKSci J95463
 
 
Loading Please Wait...
  J95463    AKSci Bulk Reagent
7-(2,3-Dihydroxypropyl)theophylline, 95%
 
Dyphylline
Dilor
Diprophylline
more..
IDENTITY
CAS Number:479-18-5, 52756-53-3; 68350-70-9
MDL Number:MFCD00005759
MF:C10H14N4O4
MW:254.24
EINECS:207-526-1
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:95%
Physical Form (at 20°C):Solid
Melting Point:160-166°C
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: 51mg/mL; H2O: 50mg/mL; EtOH: <1mg/mL
Application(s):Bronchodilator Agent; Phosphodiesterase Inhibitor; Vasodilator Agent
Form:Free Base

REVIEW
 A xanthine derivative with bronchodilator and vasodilator effects. It is used in the treatment of respiratory disorders like asthma, cardiac dyspnea, and bronchitis. It acts as an adenosine receptor antagonist and phosphodiesterase inhibitor.

REFERENCES
[1]Varma MV, Obach RS, Rotter C, Miller HR, Chang G, Steyn SJ, El-Kattan A, Troutman MD (2010). Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. J Med Chem. 53(3):1098-108. PMID 20070106.
[2] Dorfmueller HC, van Aalten DM (2010). Screening-based discovery of drug-like O-GlcNAcase inhibitor scaffolds. FEBS Lett. 584(4):694-700. PMID 20026047.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H302

Precautionary Statements
P264; P270; P301+P312; P330; P501

Current as of June 26, 2022


Download SDS

For research use only. Not for diagnostic or therapeutic use. Not for human use. AK Scientific, Inc. does not sell to individuals. If you are a first-time customer, please email for review at least two official business documents issued by your local jurisdiction, state/province, or country.


CATEGORIES
 Heterocyclic Building Blocks > Purines
 Nucleobases > Purines
 Nucleobases > Purines


PubChem