479-18-5 7-(2,3-Dihydroxypropyl)theophylline AKSci J95463
 
 
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  J95463    AKSci Bulk Reagent
7-(2,3-Dihydroxypropyl)theophylline, 95%
 
Dyphylline
Dilor
Diprophylline
more..
IDENTITY
CAS Number:479-18-5
MDL Number:MFCD00005759
MF:C10H14N4O4
MW:254.24
EINECS:207-526-1
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:95%
Physical Form (at 20°C):Solid
Melting Point:160-166°C
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: 51mg/mL; H2O: 50mg/mL; EtOH: <1mg/mL
Application(s):Bronchodilator Agent; Phosphodiesterase Inhibitor; Vasodilator Agent
Form:Free Base

REVIEW
 A xanthine derivative with bronchodilator and vasodilator effects. It is used in the treatment of respiratory disorders like asthma, cardiac dyspnea, and bronchitis. It acts as an adenosine receptor antagonist and phosphodiesterase inhibitor.

REFERENCES
[1]Varma MV, Obach RS, Rotter C, Miller HR, Chang G, Steyn SJ, El-Kattan A, Troutman MD (2010). Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. J Med Chem. 53(3):1098-108. PMID 20070106.
[2] Dorfmueller HC, van Aalten DM (2010). Screening-based discovery of drug-like O-GlcNAcase inhibitor scaffolds. FEBS Lett. 584(4):694-700. PMID 20026047.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H302

Precautionary Statements
P264; P270; P301+P312; P330; P501

Current as of April 20, 2024


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⚠️
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

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CATEGORIES
 Heterocyclic Building Blocks > Purines
 Nucleobases > Purines
 Nucleobases > Purines


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