3681-99-0 Puerarin AKSci J95394
 
 
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  J95394    
Puerarin
, 95%
 
8-(β-D-Glucopyranosyl-7-hydroxy-3- (4-hydroxyphenyl)-4H-1-benzopyran-4-one




IDENTITY
CAS Number:3681-99-0
MDL Number:MFCD00063399
MF:C21H20O9
MW:416.38
BRN:64198
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:95%
Physical Form:White powder
Melting Point:187-189°C
Optical Rotation:19° (c=1, methanol)
Long-Term Storage:Store long-term at 2-8°C
HAZARDOUS MATERIALS INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:Soluble in methanol, and DMSO
Application(s):5-HT2C receptor and benzodiazepine site antagonist, a flavonoid derivative with potential antioxidan

REVIEW

 Puerarin is a flavonoid derivative from the traditional oriental medicine, Ge-gen. Purarin has potential antioxidant activity and impairs CYP catalyzed drug metabolism. A metabolite, calycosin, shows cytotoxic activity.

REFERENCES
[1]Kim, D.H., et al. 1998. J. Biol Pharm Bull. 21: 628-360. PMID: 9657051.
[2] Guerra, M.C., et al. 2000. Life Sci. 67: 2997-3006. PMID: 11133012.

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of June 16, 2021


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CATEGORIES

 APIs and Bioactives > Flavonoids


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