REVIEW Pseudopelletierine oxime, the oxime of 3-tropinone, is a key intermediate in the synthesis of Dolasetron (dolasetron mesilate) a 5-HT3 antagonist.
Putney, Blake F.; Soine, Taito O.; A synthesis of pseudopelletierine, Journal of the American Pharmaceutical Association (1912-1977) (1955), 44, 17-22.
Hadley, Michael Stewart; King, Francis David Azabicycloalkyl derivatives and pharmaceutical compositions containing them. Eur. Pat. Appl. (1980), EP 13138 A1 19800709.
Smith, Gillian Elizabeth. Process for the production of aminoazabicycloalkanes from oximes. PCT Int. Appl. (1996), WO 9603401 A2 19960208.
Vernekar, Sanjeev Kumar V.; Hallaq, Hasan Y.; Clarkson, Guy; Thompson, Andrew J.; Silvestri, Linda; Lummis, Sarah C. R.; Lochner, Martin Toward Biophysical Probes for the 5-HT3 Receptor: Structure-Activity Relationship Study of Granisetron Derivatives. Journal of Medicinal Chemistry (2010), 53(5), 2324-2328.
For research use only. Not for diagnostic or therapeutic use. Not for human use. AK Scientific, Inc. does not sell to individuals. If you are a first-time customer, please email for review at least two official business documents issued by your local jurisdiction, state/province, or country.