90776-59-3 beta-Methyl vinyl phosphate AKSci J94413
 
 
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  J94413    AKSci Bulk Reagent
beta-Methyl vinyl phosphate, 95%
 
(4R,5R,6S)-3-[(Diphenoxyphosphinyl)oxy]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid (4-Nitrophenyl)methyl Ester
IDENTITY
CAS Number:90776-59-3
MDL Number:MFCD01318092
MF:C29H27N2O10P
MW:594.51
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:95%
Physical Form (at 20°C):Solid
Melting Point:126-130°C
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

REVIEW
 An advanced carbopenem intermediate used in the preparation of various antibiotics.

REFERENCES
[1]Nakajima, Yoshihiro; Hara, Tamio Preparation of p-nitrobenzyl (4R,5R,6S)-3-diphenylphosphoryloxy-6-[(R)-1-hydroxyethyl]-4-methyl-7- oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate as antibiotic 1beta-carbapenem intermediate intermediate Jpn. Kokai Tokkyo Koho (1996), JP 08311092 A 19961126.
[2] Nishino, Keita; Koga, Teruyoshi; Fukae, Masafumi; Ueda, Yasuyoshi Improved method for the crystallization of intermediate of carbapenem antibiotics PCT Int. Appl. (2007), WO 2007125788 A1 20071108.
[3] Okue, Masayuki; Takahashi, Masaaki; Ishikawa, Ichiro; Ito, Nobuo; Yamaguchi, Hitoshi; Sumi, Shinjiro; Ajito, Keiichi Method for producing 1-methylcarbapenem intermediate PCT Int. Appl. (2008), WO 2008020597 A1 20080221.
[4] Okue, Masayuki; Takahashi, Masaaki; Ishikawa, Ichiro; Ito, Nobuo; Yamaguchi, Hitoshi; Sumi, Shinjiro; Ajito, Keiichi Method for producing 1-methylcarbapenem intermediate PCT Int. Appl. (2008), WO 2008020597 A1 20080221.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of April 19, 2024


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⚠️
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CATEGORIES
 APIs and Bioactives > Carbapenems


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