61336-70-7 Amoxicillin trihydrate AKSci J93454
 
 
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  J93454    AKSci Bulk Reagent
Amoxicillin trihydrate, 95%
 
Amoxicillin
Larotid
Amoxil
more..
IDENTITY
CAS Number:61336-70-7
MDL Number:MFCD00072029
MF:C16H25N3O8S
MW:419.45
EINECS:243-003-8
BRN:7507120
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:95%
Physical Form (at 20°C):Solid
Melting Point:197-204°C
Optical Rotation:+290° - +315° (c=0.1, H2O)
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:H2O: 4mg/mL; EtOH: 3.4mg/mL; MeOH: 7.5mg/mL
Application(s):Antibiotic
Form:Hydrate

REVIEW
 Beta-lactam antibiotic used to treat bacterial infections caused by susceptible microorganisms. The drug acts by inhibiting the synthesis of bacterial cell walls. It inhibits cross-linkage between the linear peptidoglycan polymer chains that make up a major component of the cell walls of both Gram-positive and Gram-negative bacteria.

REFERENCES
[1]Xie K, Jia L, Xu D, Guo H, Xie X, Huang Y, Chen X, Bao W, Dai G, Wang J (2012). Simultaneous determination of amoxicillin and ampicillin in eggs by reversed-phase high-performance liquid chromatography with fluorescence detection using pre-column derivatization. J Chromatogr Sci. 50(7):620-4. PMID 22562818.
[2] Ji C, Miller PA, Miller MJ (2012). Iron transport-mediated drug delivery: practical syntheses and in vitro antibacterial studies of tris-catecholate siderophore-aminopenicillin conjugates reveals selectively potent antipseudomonal activity. J Am Chem Soc. 134(24):9898-901. PMID 22656303.
[3] AK Hilton.; PB Deasy. Use of hydroxypropyl methylcellulose acetate succinate in an enteric polymer matrix to design controlled-release tablets of amoxicillin trihydrate. Journal of Pharmaceutical Sciences. 1993, 82, (7), 737-743.
[4] SK Yellanki.; J Singh.; JA Syed.; R Bigala. Design and characterization of amoxicillin trihydrate mucoadhesive microspheres for prolonged gastric retention. International Journal of Pharmaceutical Sciences and Drug Research. 2010, 2, (2), 112-114.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Danger

Hazard Statements
H317; H334

Precautionary Statements
P261; P272; P280; P285; P302+P352; P304+P341; P321; P333+P313; P342+P311; P363; P501

RELATED PRODUCTS
F637Amoxicillin sodium
Q787Amoxicillin trihydrate

Current as of May 15, 2024


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⚠️
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.


CATEGORIES
 APIs and Bioactives > Antibacterials, Penicillins


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