877399-52-5 Crizotinib AKSci J93044
 
 
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  J93044    
Crizotinib
, 95%
 
PF-02341066, (R)-3-[1-(2,6-Dichloro-3-fluoro-phenyl)-ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)-pyridin-2-ylamine




IDENTITY
CAS Number:877399-52-5
MDL Number:MFCD12407409
MF:C21H22Cl2FN5O
MW:450.34
SPECIFICATIONS & PROPERTIES
Purity:95%
Physical Form:Beige powder
Melting Point:197-203°C
Density:1.475
Refractive Index:1.673
Long-Term Storage:Store at room temperature

BIOLOGICAL INFO
Application(s):c-Met and ALK inhibitor

REVIEW

 Crizotinib is a potent inhibitor of c-Met and ALK with IC50 of 11 nM and 24 nnM, respectivley.

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of March 18, 2019


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CATEGORIES

 APIs and Bioactives > Protein Kinase Inhibitors


PubChem