148-24-3 8-Hydroxyquinoline AKSci J92443
 
 
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  J92443    AKSci Bulk Reagent
8-Hydroxyquinoline
, 95%
 
Oxyquinoline
Oxine
8-Quinolinone
more..




IDENTITY
CAS Number:148-24-3
MDL Number:MFCD00006807
MF:C9H7NO
MW:145.16
EINECS:205-711-1
BRN:114512
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:95%
Physical Form (at 20°C):Solid
Melting Point:70-76°C
Boiling Point:267°C (752mmHg)
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:Almost insoluble in water and diethyl ether; Highly soluble in ethanol, acetone, chloroform, and benzene
Application(s):Transcription inhibitor

REVIEW

 8-Hydroxyquinoline is an antiseptic with mild fungistatic, bacteriostatic, anthelmintic, and amebicidal action. It has also been used as a reagent and metal chelator, as a carrier for radio-indium for diagnostic purposes, and its halogenated derivatives are used as topical anti-infective agents and oral antiamebics. The metal chelation complexes as well as the heterocycle itself exhibit antiseptic, disinfectant, and pesticide properties, functioning as a transcription inhibitor. Its solution in alcohol is used in liquid bandages. It once was of interest as an anti-cancer drug.

REFERENCES
[1]Prachayasittikul V, Prachayasittikul S, Ruchirawat S, Prachayasittikul V. 8-Hydroxyquinolines: a review of their metal chelating properties and medicinal applications. Drug Des Devel Ther. 2013 Oct 4;7:1157-1178.
[2] Neldner KH.The halogenated 8-hydroxyquinolines. Int J Dermatol. 1977 May;16(4):267-73.
[3] Pierre JL, Baret P, Serratrice G. Hydroxyquinolines as iron chelators. Curr Med Chem. 2003 Jun;10(12):1077-84.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H302; H402

Precautionary Statements
P264; P270; P273; P301+P312+P330; P501


RELATED PRODUCTS
A0488-Hydroxyquinoline
I9738-Hydroxyquinoline sulfate

Current as of October 16, 2024


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All batches backed with full quality assurance.
⚠️
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.



CATEGORIES

 APIs and Bioactives > Antibacterials, Fungicides
 Heterocyclic Building Blocks > Quinolines, Alcohols
  Reagents > Chelation


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