53-16-7 Estrone AKSci J90629
 
 
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  J90629    
Estrone, 95%
 
3-Hydroxy-1,3,5(10)-estratrien-17-one
1,3,5(10)-Estratrien-3-ol-17-one
Folliculin Oestrone
IDENTITY
CAS Number:53-16-7
MDL Number:MFCD00003620
MF:C18H22O2
MW:270.37
EINECS:200-164-5
BRN:1915077
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:95%
Physical Form:White to off-white crystalline powder
Melting Point:258-263°C
Optical Rotation:+158° to +165° (c=1, Dioxane)
Long-Term Storage:Store at room temperature
HAZARDOUS MATERIALS INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: 54mg/mL; H2O: <1mg/mL; EtOH: <1mg/mL
Application(s):Estrogen receptor
Form:Free Base

REVIEW
 An estrogenic hormone secreted by the ovary as well as adipose tissue.

REFERENCES
[1]Axon A, May FE, Gaughan LE, Williams FM, Blain PG, Wright MC (2012). Tartrazine and sunset yellow are xenoestrogens in a new screening assay to identify modulators of human oestrogen receptor transcriptional activity. Toxicology. 298(1-3):40-51. PMID 22562034.
[2] Engler-Chiurazzi EB, Talboom JS, Braden BB, Tsang CW, Mennenga S, Andrews M, Demers LM, Bimonte-Nelson HA (2012). Continuous estrone treatment impairs spatial memory and does not impact number of basal forebrain cholinergic neurons in the surgically menopausal middle-aged rat. Horm Behav. 62(1):1-9. PMID 22522079.

GHS

Pictograms

Signal Word
Danger

Hazard Statements
H350; H360

Precautionary Statements
P201; P202; P281; P308+P313; P405; P501

Current as of March 3, 2021


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For research use only. Not for diagnostic or therapeutic use. Not for human use. AK Scientific, Inc. does not sell to individuals. If you are a first-time customer, please email for review at least two official business documents issued by your local jurisdiction, state/province, or country.

WARNING: Attention California residents: This product can expose you to chemicals including Estrone, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.


CATEGORIES
 APIs and Bioactives > Steroid Hormones


PubChem