53-16-7 Estrone AKSci J90629
 
 
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  J90629    AKSci Bulk Reagent
Estrone, 95%
 
3-Hydroxy-1,3,5(10)-estratrien-17-one
1,3,5(10)-Estratrien-3-ol-17-one
Folliculin Oestrone
IDENTITY
CAS Number:53-16-7
MDL Number:MFCD00003620
MF:C18H22O2
MW:270.37
EINECS:200-164-5
BRN:1915077
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:95%
Physical Form (at 20°C):Solid
Melting Point:258-263°C
Optical Rotation:+158° to +165° (c=1, Dioxane)
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: 54mg/mL; H2O: <1mg/mL; EtOH: <1mg/mL
Application(s):Estrogen receptor
Form:Free Base

REVIEW
 An estrogenic hormone secreted by the ovary as well as adipose tissue.

REFERENCES
[1]Axon A, May FE, Gaughan LE, Williams FM, Blain PG, Wright MC (2012). Tartrazine and sunset yellow are xenoestrogens in a new screening assay to identify modulators of human oestrogen receptor transcriptional activity. Toxicology. 298(1-3):40-51. PMID 22562034.
[2] Engler-Chiurazzi EB, Talboom JS, Braden BB, Tsang CW, Mennenga S, Andrews M, Demers LM, Bimonte-Nelson HA (2012). Continuous estrone treatment impairs spatial memory and does not impact number of basal forebrain cholinergic neurons in the surgically menopausal middle-aged rat. Horm Behav. 62(1):1-9. PMID 22522079.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Danger

Hazard Statements
H350; H360

Precautionary Statements
P201; P202; P281; P308+P313; P405; P501

Current as of September 30, 2022


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⚠️
These chemical products are for research and development use only. They are not for diagnostic, therapeutic, cosmetic, or human and animal uses. They are not sold to individuals. Additional restrictions may apply.
New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information.
⚠️

WARNING: Attention California residents: This product can expose you to chemicals including Estrone, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.



CATEGORIES
 APIs and Bioactives > Steroid Hormones


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