123171-59-5 Cefepime dihydrochloride monohydrate AKSci J90121
 
 
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  J90121    AKSci Bulk Reagent
Cefepime dihydrochloride monohydrate
, 95%
 



IDENTITY
CAS Number:123171-59-5
MDL Number:MFCD01687679
MF:C19H24N6O5S2.2HCl.H2O
MW:571.50
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:95%
Physical Form (at 20°C):Solid
Melting Point:195-203°C
Long-Term Storage:Store long-term at -20°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: 12mg/mL; H2O: 2mg/mL
Application(s):A fourth generation cephalosporin antibacterial

REVIEW

 Cephalosporins are bactericidal and have the same mode of action as other beta-lactam antibiotics (such as penicillins). Cephalosporins disrupt the synthesis of the peptidoglycan layer of bacterial cell walls. The peptidoglycan layer is important for cell wall structural integrity, especially in Gram-positive organisms. The final transpeptidation step in the synthesis of the peptidoglycan is facilitated by transpeptidases known as penicillin binding proteins (PBPs).

REFERENCES
[1]Chapman TM, Perry CM: Cefepime: a review of its use in the management of hospitalized patients with pneumonia. Am J Respir Med. 2003;2(1):75-107.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H334; H317

Precautionary Statements
P285; P261; P280; P342+P311; P363; P304+P341; P321; P333+P313; P302+P352; P501


Current as of October 16, 2024


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CATEGORIES

 APIs and Bioactives > Antibacterials, Cephalosporins


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