87333-19-5 Ramipril AKSci J90014
 
 
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  J90014    AKSci Bulk Reagent
Ramipril, 95%
 
Tritace
Altace
[2S,3aS,6aS]-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid
IDENTITY
CAS Number:87333-19-5
MDL Number:MFCD00865775
MF:C23H32N2O5
MW:416.51
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:95%
Physical Form (at 20°C):Solid
Melting Point:109-117°C
Optical Rotation:+13 ~ +17° (c=1, MeOH)
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: 83mg/mL; H2O: <1mg/mL; EtOH: 83mg/mL
Application(s):Angiotensin-converting enzyme (ACE) inhibitor; Antihypertensive Agent
Form:Free Base

REVIEW
 Ramipril is an angiotensin-converting enzyme (ACE) inhibitor that is used to treat high blood pressure and congestive heart failure.

REFERENCES
[1]Cacciapuoti F, Capasso A, Mirra G, De Nicola A, Minicucci F, Gentile S: Prevention of left ventricular hypertrophy by ACE-inhibitor, ramipril in comparison with calcium-channel antagonist, felodipine. Int J Cardiol. 1998 Jan 31;63(2):175-8.
[2] Kleinert S: HOPE for cardiovascular disease prevention with ACE-inhibitor ramipril. Heart Outcomes Prevention Evaluation. Lancet. 1999 Sep 4;354(9181):841.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of March 21, 2023


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⚠️
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CATEGORIES
 APIs and Bioactives > ACE Inhibitors


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