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BIOLOGICAL INFO
Solubility:
DMSO: <1mg/mL; H2O: <1mg/mL; EtOH: <1mg/mL
Application(s):
DNA/RNA Synthesis
Form:
Free Base
REVIEW A nucleobase (a purine derivative) with a variety of roles in biochemistry including cellular respiration, in the form of both the energy-rich adenosine triphosphate (ATP) and the cofactors nicotinamide adenine dinucleotide (NAD) and flavin adenine dinucleotide (FAD), and protein synthesis, as a chemical component of DNA and RNA
REFERENCES
[1]
Bchini R, Dubourg-Gerecke H, Rahuel-Clermont S, Aubry A, Branlant G, Didierjean C, Talfournier F (2012). Adenine binding mode is a key factor in triggering the early release of NADH in coenzyme A-dependent methylmalonate semialdehyde dehydrogenase .J Biol Chem. 287(37):31095-103. PMID 22782904.
[2]
Liu Z, Guo X, Tan C, Li J, Kao YT, Wang L, Sancar A, Zhong D (2012). Electron tunneling pathways and role of adenine in repair of cyclobutane pyrimidine dimer by DNA photolyase. J Am Chem Soc. 134(19):8104-14. PMID 22533849.
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