73-24-5 Adenine AKSci J70183
 
 
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  J70183    
Adenine
, 98% (HPLC)
 
6-Aminopurine
1H-Purin-6-amine
9H-Purin-6-amine




IDENTITY
CAS Number:73-24-5
MDL Number:MFCD00041790
MF:C5H5N5
MW:135.13
EINECS:200-796-1
BRN:5777
SPECIFICATIONS & PROPERTIES
Purity:98% (HPLC)
Physical Form:White to off-white to light yellow to yellow powder
Melting Point:>350°C
Long-Term Storage:Store at room temperature
UN #:UN2811
Hazard Class:6.1; Poison
Packing Group:III

BIOLOGICAL INFO
Solubility:DMSO: <1mg/mL; H2O: <1mg/mL; EtOH: <1mg/mL
Application(s):DNA/RNA Synthesis
Form:Free Base

REVIEW

 A nucleobase (a purine derivative) with a variety of roles in biochemistry including cellular respiration, in the form of both the energy-rich adenosine triphosphate (ATP) and the cofactors nicotinamide adenine dinucleotide (NAD) and flavin adenine dinucleotide (FAD), and protein synthesis, as a chemical component of DNA and RNA

REFERENCES
[1]Bchini R, Dubourg-Gerecke H, Rahuel-Clermont S, Aubry A, Branlant G, Didierjean C, Talfournier F (2012). Adenine binding mode is a key factor in triggering the early release of NADH in coenzyme A-dependent methylmalonate semialdehyde dehydrogenase .J Biol Chem. 287(37):31095-103. PMID 22782904.
[2] Liu Z, Guo X, Tan C, Li J, Kao YT, Wang L, Sancar A, Zhong D (2012). Electron tunneling pathways and role of adenine in repair of cyclobutane pyrimidine dimer by DNA photolyase. J Am Chem Soc. 134(19):8104-14. PMID 22533849.

GHS

Pictograms

Signal Word
Danger

Hazard Statements
H301

Precautionary Statements
P264; P270; P301+P310; P321; P330; P405; P501


RELATED PRODUCTS
A265Adenine phosphate
D124Adenine
E026Adenine sulfate

Current as of July 11, 2020


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CATEGORIES

 Heterocyclic Building Blocks > Purines, Amines
 Nucleobases > Primary Nucleobases
 Nucleobases > Primary Nucleobases


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