81810-66-4, 850339-82-1 Quinocetone AKSci J62519
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, 95%

CAS Number:81810-66-4, 850339-82-1
MDL Number:MFCD09753267
Min. Purity Spec:95%
Physical Form (at 20°C):Solid
Melting Point:199-203°C
Refractive Index:1.62
Long-Term Storage:Store long-term in a cool, dry place
Not hazardous material


 Quinocetone is a quinoxaline-N,N-dioxide antimicrobial agent used in veterinary medicine as a feed additive for livestock, birds and fish. It is an antidiarrheal growth promotion drug developed in Lanzhou, China. Quinocetone has also been seen to induce a decline in aldosterone production from the swine adrenal glands in vivo and in vitro, and thus cause hypovolemia, hyponatremia and hyperkalemia. The compound is under investigation for potential benefits against aldosterone dysmetabolism disease via the reduction of aldosterone production in adrenal and/or the cardiovascular tissues. This may provide a new option in the therapy for aldosterone dysmetabolism disease, especially in the cardiovascular system.

[1]Benko, Pal; Bozsing, Daniel; Gundel, Janos; Magyar, Karoly noxalin-2-yl ethenyl ketones and animal feeds containing them Fr. Demande (1981), FR 2483415 A1 19811204.
[2] Zhao, Rongcai; Wang, Yuchun; Xu, Zhongzan; Xue, Feiqun; Li, Jinshan; Yan, Bolin; Du, Xiaoli; Liang, Jianping; Zhang, Jiyu; Li, Jianyong Synthesis of 3-methyl-2-cinnamoylquinoxaline 1,4-dioxide as feed additive Faming Zhuanli Shenqing Gongkai Shuomingshu (1998), CN 1197068 A 19981028.
[3] Li, Jianyong; Zhao, Rongcai; Li, Jinshan; Lu, Runhua Quincetone growth promoter in fat chicklings Indian Veterinary Journal (2005), 82(11), 1149-1151.
[4] Li, Jianyong; Zhang, Jiyu; Li, Jinshan; Xu, Zhongzan; Zhao, Rongcai; Zhou, Xuzheng the promoting effect of quinocetone on broilers Xumu Yu Shouyi (2007), 39(9), 38-40.
[5] Zheng, Zong-lin; Zhou, Yu-yan; Gong, Zhe-yu Effects of several antibiotics on growth performance and feed utilization of hybridized prussian carps Liangshi Yu Siliao Gongye (2008), (4), 31-33.
[6] Zou, Da-Jiang; Zheng, Qiao-Feng; Huang, Xian-Ju; Wang, Xu; Ihsan, Awais Potential benefits of quinoxaline 1, 4-dioxides in aldosterone dysmetabolism disease - A medical hypothesis Open Journal of Animal Sciences (2011), 1(3), 121-127.



Signal Word

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of November 30, 2023

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 APIs and Bioactives > Antibacterials, Veterinary
 Specialty Chemicals > Agrochemicals
 Specialty Chemicals > Agrochemicals