51037-30-0 Acipimox AKSci J62358
 
 
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  J62358    
Acipimox, 95%
 
2-Carboxy-5-methylpyrazine 4-oxide
5-Methylpyrazinecarboxylic acid 4-oxide
5-methylpyrazine-2-carboxylic acid 4-oxide
more..
IDENTITY
CAS Number:51037-30-0
MDL Number:MFCD00865757
MF:C6H6N2O3
MW:154.12
EINECS:256-928-3
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:95%
Physical Form (at 20°C):Solid
Melting Point:177-180°C
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: 31mg/mL
Application(s):Hypolipidemic Agent
Form:Free Base

REVIEW
 Acipimox, an anti-lipoytic drug and vasodilator, is used in studies involving lipolysis. Acipimox may be used in various metabolic studies involving insulin and ghrelin.

REFERENCES
[1]Lim EL, Hollingsworth KG, Smith FE, Thelwall PE, Taylor R (2011). Inhibition of lipolysis in Type 2 diabetes normalizes glucose disposal without change in muscle glycogen synthesis rates. Clin Sci (Lond). 121(4):169-77. PMID 21388348.
[2] Montecucco F, Bertolotto M, Vuilleumier N, Franciosi U, Puddu A, Minetti S, Delrio A, Quercioli A, Bergamini E, Ottonello L, Pende A, Lenglet S, Pelli G, Mach F, Dallegri F, Viviani GL (2011). Acipimox reduces circulating levels of insulin and associated neutrophilic inflammation in metabolic syndrome. Am J Physiol Endocrinol Metab. 300(4):E681-90. PMID 21266669.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H319

Precautionary Statements
P264; P280; P305+P351+P338; P337+P313

Current as of April 20, 2024


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⚠️
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CATEGORIES
 APIs and Bioactives > Hypercholesterolemia


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