REVIEW A key intermediate used in the synthesis of the side chain portion of carbopenem antibiotics such as biapenem.
REFERENCES
[1]
Wildonger, Kenneth J.; Ratcliffe, Ronald W. Heteroaryliumthio substituted carbapenem derivatives: synthesis and in vitro activity of 1β-methyl-2-(dihydropyrrolotriazoliumthio)carbapenems Journal of Antibiotics (1993), 46(12), 1866-82.
[2]
Sano, Atsunori; Sumino, Motoshige; Tani, Tsutomu Preparation of 6,7-dihydro-5H-pyrazolo[1,2-a][1,2,4]triazolium salts as intermediates for carbapenems Jpn. Kokai Tokkyo Koho (1995), JP 07076585 A 19950320.
[3]
Kumagai, Toshio; Tamai, Satoshi; Abe, Takao; Matsunaga, Hiroshi; Hayashi, Kazuhiko; Kishi, Ikuo; Shiro, Motoo; Nagao, Yoshimitsu New Straightforward Synthesis and Characterization of a Unique 1β-Methylcarbapenem Antibiotic Biapenem Bearing a s-Symmetric Bicyclotriazoliumthio Group as the Pendant Moiety Journal of Organic Chemistry (1998), 63(23), 8145-8149.
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