6153-33-9 Mebhydroline napadisylate AKSci J61824
 
 
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  J61824    
Mebhydroline napadisylate
, 95%
 
9-Benzyl-N-methyl-1,2,3,4-tetrahydro-a-carboline, Mebhydroline 1,5-naphthalenedisulfonate salt




IDENTITY
CAS Number:6153-33-9
MDL Number:MFCD00083420
MF:C48H48N4O6S2
MW:841.05
EINECS:228-170-3
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:95%
Physical Form (at 20°C):Solid
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Application(s):H1 Histamine receptor antagonist
Form:Salt

REVIEW

 Mebhydrolin is an antihistamine. It is in available in various countries, but not in the U.S. It is used for symptomatic relief of allergic symptoms caused by histamine release, including nasal allergies and allergic dermatosis. Mebhydrolin has been shown to enhance the performance-deficit effects of alcohol.

REFERENCES
[1]Kharkevich, D. A. Pharmacology of diazoline Farmakologiya i Toksikologiya (Moscow) (1957), 20(No. 6), 46-51.
[2] Guzzetti R, Saggiorato F. Efficacy and tolerance to mebhydroline in comparison with dimetindene maleate]. Clin Ter. 1986 Jan 31;116(2):109-14.
[3] Dorittke P, Wassilew SW. Sneddon Wilkinson subcorneal pustulosis, therapy with mebhydroline. Z Hautkr. 1988 Dec 15;63(12):1025-7.
[4] Waitzinger J, Lenders H, Pabst G, Reh C, Ulbrich E. Three explorative studies on the efficacy of the antihistamine mebhydroline (Omeril). Int J Clin Pharmacol Ther. 1995 Jul;33(7):373-83.
[5] Franks HM, Lawrie M, Schabinsky VV, Starmer GA, Teo RK. Interaction between ethanol and antihistamines: 3. mebhydrolin.Med J Aust. 1981 Oct 31;2(9):477-9.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of April 20, 2024


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⚠️
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These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

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CATEGORIES

 APIs and Bioactives > Antihistamines


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