107753-78-6 Zafirlukast AKSci J61771
 
 
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  J61771    
Zafirlukast, 95%
 
N-[3-[[2-Methoxy-4-[[[(2-methylphenyl)sulfonyl]amino]carbonyl]phenyl]methyl]-1-methyl-1H-indol-5-yl]carbamic acid cyclopentyl ester

Structure N/A
IDENTITY
CAS Number:107753-78-6
MDL Number:MFCD00864775
MF:C31H33N3O6S
MW:575.68
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:95%
Physical Form (at 20°C):Solid
Melting Point:138-140°C
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: >=28 mg/mL
Application(s):Leukotriene receptor antagonist (LTRA)

REVIEW
 Zafirlukast is a selective and competitive receptor antagonist of leukotriene D4 and E4 (LTD4 and LTE4), components of slow-reacting substance of anaphylaxis (SRSA). Cysteinyl leukotriene production and receptor occupation have been correlated with the pathophysiology of asthma, including airway edema, smooth muscle constriction, and altered cellular activity associated with the inflammatory process, which contribute to the signs and symptoms of asthma.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H413

Precautionary Statements
P273; P501

Current as of March 25, 2023


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CATEGORIES
 APIs and Bioactives > Leukotrine Receptor Antagonists


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