60200-06-8 Clorsulon AKSci J61672
 
 
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  J61672    
Clorsulon, 95%
 
4-Amino-6-(trichlorovinyl)-1,3-benzenedisulfonamide
Curatrem
IDENTITY
CAS Number:60200-06-8
MDL Number:MFCD00072006
MF:C8H8Cl3N3O4S2
MW:380.66
EINECS:262-100-2
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:95%
Physical Form (at 20°C):Solid
Melting Point:194-205°C
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Application(s):Anthelmintic; Antiplatyhelmintic Agent
Form:Free Base

REVIEW
 Clorsulon is a specific, narrow-spectrum flukicide anthelmintic and endoparasiticide used on ruminants livestock. It is usually only available in combination with ivermectin. It inhibits enzymes in the glycolytic pathway, depressing ATP levels in target flukes.

REFERENCES
[1]Mrozik, Helmut H. Substituted benzenedisulfonamides Ger. Offen. (1976), DE 2556122 A1 19760624.
[2] Helmut Mrozik , Richard J. Bochis , Philip Eskola , Alexander Matzuk , Frank S. Waksmunski , Leonard E. Olen , George Schwartzkopf Jr., Alex Grodski , Bruce O. Linn 4-Amino-6-(trichloroethenyl)-1,3-benzenedisulfonamide, a new, potent fasciolicide Journal of Medicinal Chemistry (1977), 20(9), 1225-7.
[3] Hutchinson GW, Dawson K, Fitzgibbon CC, Martin PJ (2009). Efficacy of an injectable combination anthelmintic (nitroxynil+clorsulon+ivermectin) against early immature Fasciola hepatica compared to triclabendazole combination flukicides given orally or topically to cattle. Vet Parasitol. 162(3-4):278-84. PMID 19375232.
[4] Meaney M, Fairweather I, Brennan GP, Forbes AB (2004). Transmission electron microscope study of the ultrastructural changes induced in the tegument and gut of Fasciola hepatica following in vivo drug treatment with clorsulon. Parasitol Res. 92(3):232-41. PMID 14714178.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of April 24, 2024


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All products are stocked and shipped from San Francisco Bay Area, California, USA.

⚠️
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.


CATEGORIES
 APIs and Bioactives > Antiparasitics, Veterinary


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