20559-55-1 Oxibendazole AKSci J61579
 
 
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  J61579    
Oxibendazole
, 95%
 
Methyl (5-propoxy-1H-benzimidazol-2-yl)carbamate




IDENTITY
CAS Number:20559-55-1
MDL Number:MFCD00133728
MF:C12H15N3O3
MW:249.27
EINECS:243-877-7
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:95%
Physical Form (at 20°C):Solid
Melting Point:230-231°C
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:water:insoluble;
Application(s):Broad-spectrum anthelmintic

REVIEW

 Oxibendazole is a benzimidazole antiparasitic drug used to protect against roundworms, strongyles, threadworms, pinworms and lungworm infestations in horses and domestic pets. It binds to beta-tubulin and prevents the polymerization of the microtubules, impairing intracellular transport mechanisms and interfering with protein synthesis.

REFERENCES
[1]Karunakaran CS, Denham DA. J Parasitol. 66:929-32 (1980).
[2] Theodorides VJ, DiCuollo CJ, Nawalinski T et al. Am J Vet Res. 38:809-14 (1977).
[3] Anthelmintic benzimidazoles Brit. (1968), GB 1123317 19680814.
[4] Richard J. Bochis , Leonard E. Olen , Frank S. Waksmunski , Helmut Mrozik , Philip Eskola , Peter Kulsa , George Wilks , Joyce E. Taylor , John R. Egerton Substituted imidazo[1,2-a]pyridine-2-carbamate anthelmintics Journal of Medicinal Chemistry (1981), 24(12), 1518-21.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
None

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of October 9, 2024


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These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

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CATEGORIES

 APIs and Bioactives > Antiparasitics


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