151767-02-1 Montelukast sodium AKSci J55163
 
 
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  J55163    
Montelukast sodium
, 95%
 
1-[[[(1R)-1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic acid sodium salt hydrate




IDENTITY
CAS Number:151767-02-1
MDL Number:MFCD00931431
MF:C35H35ClNNaO3S
MW:608.17
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:95%
Physical Form (at 20°C):Solid
Melting Point:84-90°C
Optical Rotation:+95.0° - +105.0° (c=1, MeOH)
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: =8 mg/mL at 60 °C
Application(s):Receptor antagonist (LTRA)

REVIEW

 Montelukast selectively antagonizes leukotriene D4 (LTD4) at the cysteinyl leukotriene receptor, CysLT1, in the human airway. Montelukast inhibits the actions of LTD4 at the CysLT1 receptor, preventing airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of September 29, 2022


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⚠️
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CATEGORIES

 APIs and Bioactives > Leukotrine Receptor Antagonists


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