91374-20-8 Ropinirole HCl AKSci J52529
 
 
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  J52529    
Ropinirole HCl
, 97%
 
4-[2-(Dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one hydrochloride, SKF 101468 hydrochloride

Structure N/A

IDENTITY
CAS Number:91374-20-8
MDL Number:MFCD01754173
MF:C16H25ClN2O
MW:296.84
SPECIFICATIONS & PROPERTIES
Purity:97%
Physical Form:Light yellow powder
Melting Point:235-243°C
Long-Term Storage:Store at room temperature

BIOLOGICAL INFO
Solubility:H2O: >10 mg/mL
Application(s):Selective dopamine D2 receptors inhibitor
Form:HCl salt

REVIEW

 Ropinirole binds the dopamine receptors D3 and D2. Although the precise mechanism of action of ropinirole as a treatment for Parkinson's disease is unknown, it is believed to be related to its ability to stimulate these receptors in the striatum. This conclusion is supported by electrophysiologic studies in animals that have demonstrated that ropinirole influences striatal neuronal firing rates via activation of dopamine receptors in the striatum and the substantia nigra, the site of neurons that send projections to the striatum.

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H302; H410

Precautionary Statements
P264; P270; P273; P301+P312; P330; P391; P501


Current as of October 17, 2019


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For research use only. Not for diagnostic or therapeutic use.
Not for human use.


CATEGORIES

 APIs and Bioactives > Dopamine Agonists


PubChem