53994-69-7 7-ACCA AKSci J52509
 
 
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  J52509    AKSci Bulk Reagent
7-ACCA, 95%
 
7-Amino-3-chloro-3-cephem-4-carboxylic Acid, 7-Amino-3-chlorocephalosporanic acid
IDENTITY
CAS Number:53994-69-7
MDL Number:MFCD09039101
MF:C7H7ClN2O3S
MW:234.66
EINECS:258-907-4
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:95%
Physical Form (at 20°C):Solid
Melting Point:230°C (dec.)
Density:1.81
Refractive Index:1.73
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

REVIEW
 Bicyclic beta-lactam used as a key intermediate for the preparation of Cefaclor, a second-generation cephalosporin antibiotic used to treat certain infections caused by bacteria such as pneumonia and ear, lung, skin, throat, and urinary tract infections.

REFERENCES
[1]Sci Prog. 2013;96(Pt 1):19-32.
[2] R Zeng, J Huang, Lv, W Dexin; F Wang, Method for preparation of Cefaclor, Faming Zhuanli Shenqing (2012), CN 102796120 A 20121128.
[3] Y-W Zhang, D-Z Wei, Enzymatic Preparation of Cefaclor with Immobilized Penicillin Acylase, Preparative Biochemistry & Biotechnology (2008), 38(2), 129-138@HM Moody,; TJ Van Dooren, M Godfried, Process for the synthesis of cefaclor, PCT Int. Appl. (2006), WO 2006069984 A2 20060706@T Glinka, K Huie, A Cho, M Ludwikow, J Blais, D Griffith, S Hecker M Dudley, Relationships between structure, antibacterial activity, serum stability, pharmacokinetics and efficacy in 3-(heteroarylthio)cephems. Discovery of RWJ-333441 (MC-04,546), Bioorganic & Medicinal Chemistry (2003), 11(4), 591-600.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of October 9, 2024


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⚠️
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CATEGORIES
 APIs and Bioactives > Cephalosporins


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