81732-46-9 Bambuterol HCl AKSci J51858
 
 
Loading Please Wait...
  J51858    
Bambuterol HCl, 95%
 
Bambec, Oxeol
IDENTITY
CAS Number:81732-46-9
MDL Number:MFCD03427293
MF:C18H30ClN3O5
MW:403.9
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:95%
Physical Form (at 20°C):Solid
Melting Point:221-232°C
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:H2O: soluble -33mg/mL
Application(s):beta-adrenoceptor agonist
Form:HCl salt

REVIEW
 Inhibits plasma cholinesterase during metabolism. Bambuterol is a racemic phenylethanolamine based long acting beta-adrenoceptor agonist, used in the treatment of asthma; it also is a biscarbamate ester prodrug of the beta 2 adrenergic agonist terbutaline.

REFERENCES
[1]Olsson, Otto Agne; Svensson, Leif Ake; Wetterlin, Kjell Ingvar Leopold 1-(Dihydroxyphenyl)-2-aminoethanol derivatives, their compositions and intermediates Eur. Pat. Appl. (1982), EP 43807 A2 19820113.
[2] Svensson LA.Bambuterol- a prodrug-prodrug with built-in hydrolysis brake. Acta Pharm Suec. 1987;24(6):333-41.
[3] Svensson LA.Mechanism of action of bambuterol: a beta-agonist prodrug with sustained lung affinity. Agents Actions Suppl. 1991;34:71-8.
[4] Sitar DS.Clinical pharmacokinetics of bambuterol.Clin Pharmacokinet. 1996 Oct;31(4):246-56.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of December 8, 2023


Download SDS Request COA

⚠️
These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.


CATEGORIES
 APIs and Bioactives > Beta Blockers


PubChem
  @PubMed