REVIEW Ponazuril is a triazinedione drug approved for the treatment of equine protozoal myeloencephalitis caused by Sarcocystis neurona. It has also been used in smaller animals against coccidia.
REFERENCES
[1]
Ponazuril is a triazinedione drug currently approved for the treatment of equine protozoal myeloencephalitis caused by Sarcocystis neurona. More recently, veterinarians have been preparing a formulary version of the medication for use in small animals such as cats and dogs against coccidia, an intestinal parasite.
[2]
Kennedy, Thomas J. Triazineone compounds for treating diseases due to Sarcosystis, Neospora and Toxoplasma PCT Int. Appl. (2000), WO 2000037063 A2 20000629.
[3]
Gottstein B, Eperon S, Dai WJ, Cannas A, Hemphill A, Greif G. Efficacy of toltrazuril and ponazuril against experimental Neospora caninum infection in mice. Parasitol Res. 2001 Jan;87(1):43-8.
[4]
Kritzner S, Sager H, Blum J, Krebber R, Greif G, Gottstein B.An explorative study to assess the efficacy of toltrazuril-sulfone (ponazuril) in calves experimentally infected with Neospora caninum. Ann Clin Microbiol Antimicrob. 2002 Oct 18;1:4.
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