53797-35-6 Ribostamycin sulfate salt AKSci J51266
 
 
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  J51266    AKSci Bulk Reagent
Ribostamycin sulfate salt
, 95%
 
Ribostamycin sulfate




IDENTITY
CAS Number:53797-35-6
MDL Number:MFCD00057496
MF:C17H36N4O14S
MW:552.55
EINECS:258-783-1
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:95%
Physical Form (at 20°C):Solid
Melting Point:175-198°C
Flash Point:>110°C
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Application(s):Antibiotic
Form:Sulfate salt

REVIEW

 Ribostamycin is a broad-spectrum antimicrobial isolated from Streptomyces ribosifidicus. It is used in pharmacokinetic and nephrotoxicity studies. Aminoglycosides, such as ribostamycin, bind to the bacterial 30S and 50S ribosomal subunit, which inhibits the translocation of the peptidyl-tRNA from the A-site to the P-site. This causes misreading of mRNA which makes bacteria unable to make essential proteins. It also inhibits the chaperone activity of protein disulfide isomerase (PDI).

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Danger

Hazard Statements
H312+H332; H360

Precautionary Statements
P201; P202; P261; P271; P280; P302+P352; P304+P340; P308+P313; P322; P363; P405; P501


Current as of October 9, 2024


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CATEGORIES

 APIs and Bioactives > Antibacterials, Aminoglycosides


PubChem