52-21-1 Prednisolone acetate AKSci J50191
 
 
Loading Please Wait...
  J50191    
Prednisolone acetate, 95%
 
21-Acetoxy-1,4-pregnadiene-11beta,17alpha-diol-3,20-dione
Omnipred
Prednisolone 21-acetate
IDENTITY
CAS Number:52-21-1
MDL Number:MFCD00037710
MF:C23H30O6
MW:402.48
EINECS:200-134-1
BRN:3111798
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:95%
Physical Form:White to off-white powder
Melting Point:245-252°C
Optical Rotation:+105 ~ +118° (c=1, Dioxane)
Long-Term Storage:Store at room temperature
HAZARDOUS MATERIALS INFORMATION
UN #:UN2811
Hazard Class:6.1; Poison
Packing Group:III
A hazmat fee may apply, depending on the amount ordered.

BIOLOGICAL INFO
Solubility:CHCl3:MeOH (1:1): 50mg/mL
Application(s):Anti-Inflammatory Agent; Glucocorticoid Receptors (GR)
Form:Free Base

REVIEW
 A synthetic glucocorticoid, a derivative of cortisol, which is used to treat a variety of inflammatory and auto-immune conditions. Prednisolone irreversibly binds with glucocorticoid receptors (GR) alpha and beta for which they have a high affinity.

REFERENCES
[1]McLean NJ, Ward DA, Hendrix DV, Vaughn RK (2012). Effects of one-week versus one-day preoperative treatment with topical 1% prednisolone acetate in dogs undergoing phacoemulsification. J Am Vet Med Assoc. 240(5):563-9. PMID 22332625.
[2] Nien CJ, Flynn KJ, Chang M, Brown D, Jester JV (2011). Reducing peak corneal haze after photorefractive keratectomy in rabbits: prednisolone acetate 1.00% versus cyclosporine A 0.05%. J Cataract Refract Surg. 37(5):937-44. PMID 21406325.

GHS

Pictograms

Signal Word
Danger

Hazard Statements
H300

Precautionary Statements
P264; P270; P301+P310; P321; P330; P405; P501

Current as of April 23, 2021


Download SDS

For research use only. Not for diagnostic or therapeutic use. Not for human use. AK Scientific, Inc. does not sell to individuals. If you are a first-time customer, please email for review at least two official business documents issued by your local jurisdiction, state/province, or country.


CATEGORIES
 APIs and Bioactives > Immunomodulators


PubChem