877399-52-5 Crizotinib AKSci J20633
 
 
Loading Please Wait...
  J20633    
Crizotinib
, 98% (HPLC)
 
PF-02341066, (R)-3-[1-(2,6-Dichloro-3-fluoro-phenyl)-ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)-pyridin-2-ylamine




IDENTITY
CAS Number:877399-52-5
MDL Number:MFCD12407409
MF:C21H22Cl2FN5O
MW:450.34
SPECIFICATIONS & PROPERTIES
Purity:98% (HPLC)
Physical Form:Beige powder
Melting Point:197-203°C
Density:1.475
Refractive Index:1.673
Long-Term Storage:Store at room temperature

BIOLOGICAL INFO
Application(s):c-Met and ALK inhibitor

REVIEW

 Crizotinib is a potent inhibitor of c-Met and ALK with IC50 of 11 nM and 24 nnM, respectivley.

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H317; H319; H341; H400

Precautionary Statements
P201; P202; P261; P264; P272; P273; P280; P281; P302+P352; P305+P351+P338; P308+P313; P333+P313; P337+P313; P363; P391; P405; P501


Current as of July 2, 2020


Download SDS

For research use only. Not for diagnostic or therapeutic use. Not for human use. AK Scientific, Inc. does not sell to individuals. If you are a first-time customer, please email for review at least two official business documents issued by your local jurisdiction, state/province, or country.


CATEGORIES

 APIs and Bioactives > Protein Kinase Inhibitors


PubChem