877399-52-5 Crizotinib AKSci J20633
 
 
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  J20633    
Crizotinib
, 98% (HPLC)
 
PF-02341066, (R)-3-[1-(2,6-Dichloro-3-fluoro-phenyl)-ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)-pyridin-2-ylamine




IDENTITY
CAS Number:877399-52-5
MDL Number:MFCD12407409
MF:C21H22Cl2FN5O
MW:450.34
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:197-203°C
Density:1.475
Refractive Index:1.673
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Application(s):c-Met and ALK inhibitor

REVIEW

 Crizotinib is a potent inhibitor of c-Met and ALK with IC50 of 11 nM and 24 nnM, respectivley.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H317; H319; H341; H400

Precautionary Statements
P201; P202; P261; P264; P272; P273; P280; P281; P302+P352; P305+P351+P338; P308+P313; P333+P313; P337+P313; P363; P391; P405; P501


Current as of October 2, 2022


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⚠️
These chemical products are for research and development use only. They are not for diagnostic, therapeutic, cosmetic, or human and animal uses. They are not sold to individuals. Additional restrictions may apply.
New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information.


CATEGORIES

 APIs and Bioactives > Protein Kinase Inhibitors


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