51-60-5 Neostigmine methyl sulfate AKSci J11446
 
 
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  J11446    
Neostigmine methyl sulfate
, >98%, powder
 
3-(N,N-Dimethylcarbamoyloxy)-N,N,N,-trimethylanilinium methyl sulfate
(3-Hydroxyphenyl)trimethylammonium Methyl Sulfate Dimethylcarbamate

Structure N/A

IDENTITY
CAS Number:51-60-5
MDL Number:MFCD00011796
MF:C13H22N2O6S
MW:334.39
SPECIFICATIONS & PROPERTIES
Purity:>98%, powder
Spectra:NMR, LCMS
Physical Form:White crystalline powder
Melting Point:146-148°C
Long-Term Storage:Store long-term at 2-8°C
UN #:UN2811
Hazard Class:6.1
Packing Group:II

BIOLOGICAL INFO
Application(s):Cholinesterase inhibitor

REVIEW

 Neostigmine is a parasympathomimetic, specifically, a reversible cholinesterase inhibitor. The drug inhibits acetylcholinesterase which is responsible for the degredation of acetylcholine. So, with acetylcholinesterase inhibited, more acetylcholine is present By interfering with the breakdown of acetylcholine, neostigmine indirectly stimulates both nicotinic and muscarinic receptors which are involved in muscle contraction.. It does not cross the blood-brain barrier.

GHS

Pictograms

Signal Word
Danger

Hazard Statements
H300; H315; H319; H334; H335

Precautionary Statements
P261; P264; P270; P271; P280; P285; P301+P310; P302+P352; P304+P340; P305+P351+P338; P321; P330; P332+P313; P337+P313; P342+P311; P362; P403+P233; P405; P501


Current as of February 22, 2019


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CATEGORIES

 APIs and Bioactives > AChR Agonists


PubChem