170791-09-0 Candesartan Cilexetil EP Impurity H AKSci J11264
 
 
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  J11264    AKSci Reference Standard
Candesartan Cilexetil EP Impurity H
, 99% (HPLC)
 



IDENTITY
CAS Number:170791-09-0
MDL Number:MFCD07781274
MF:C52H48N6O6
MW:852.97
SPECIFICATIONS & PROPERTIES
Purity:99% (HPLC)
Spectra:LCMS, HPLC
Physical Form:White to off-white crystalline powder or powder
Melting Point:180-188°C
Long-Term Storage:Store long-term at 2-8°C

REVIEW

 Trityl candesartan cilexetil is an advanced intermediate used in the preparation of the prodrug candesartan cilexetil, an angiotension II receptor antagonist, used in the treatment of hypertension.

REFERENCES
[1]Naka, Takehiko; Nishikawa, Kohei; Kato, Takeshi; Preparation of benzimidazole derivatives as angiotensin II antagonists. Eur. Pat. Appl. (1991), EP 459136 A1 19911204.
[2] Etinger, Marina Yu; Fedotev, Boris; Preparation of candesartan cilexetil. PCT Int. Appl. (2005), WO 2005037821 A2 20050428.
[3] Soldevilla Madrid, Nuria; Process for preparation of candesartan cilexetil. PCT Int. Appl. (2007), WO 2007074399 A2 20070705.
[4] Wang, Ping; Tetrahedron 2010, V66(29), P5402-5406

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of July 10, 2020

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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CATEGORIES

 APIs and Bioactives > Angiotensin Receptor Blockers


PubChem
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