170791-09-0 Candesartan Cilexetil EP Impurity H AKSci J11264
 
 
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  J11264    AKSci Reference Standard
Candesartan Cilexetil EP Impurity H
, 99% (HPLC)
 



IDENTITY
CAS Number:170791-09-0
MDL Number:MFCD07781274
MF:C52H48N6O6
MW:852.97
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:99% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:180-188°C
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

REVIEW

 Trityl candesartan cilexetil is an advanced intermediate used in the preparation of the prodrug candesartan cilexetil, an angiotension II receptor antagonist, used in the treatment of hypertension.

REFERENCES
[1]Naka, Takehiko; Nishikawa, Kohei; Kato, Takeshi; Preparation of benzimidazole derivatives as angiotensin II antagonists. Eur. Pat. Appl. (1991), EP 459136 A1 19911204.
[2] Etinger, Marina Yu; Fedotev, Boris; Preparation of candesartan cilexetil. PCT Int. Appl. (2005), WO 2005037821 A2 20050428.
[3] Soldevilla Madrid, Nuria; Process for preparation of candesartan cilexetil. PCT Int. Appl. (2007), WO 2007074399 A2 20070705.
[4] Wang, Ping; Tetrahedron 2010, V66(29), P5402-5406

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of October 1, 2022

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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CATEGORIES

 APIs and Bioactives > Angiotensin Receptor Blockers


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