554-57-4 Methazolamide AKSci J11182
 
 
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  J11182    AKSci Reference Standard
Methazolamide
, 99% (HPLC)
 
Methenamide
Neptazaneat
Neptazane
more..




IDENTITY
CAS Number:554-57-4
MDL Number:MFCD00083416
MF:C5H8N4O3S2
MW:236.27
EINECS:209-066-7
SPECIFICATIONS & PROPERTIES
Purity:99% (HPLC)
Spectra:NMR, LCMS, HPLC
Physical Form:White to off-white powder
Melting Point:206-214°C
Long-Term Storage:Store at room temperature

BIOLOGICAL INFO
Application(s):Carbonic Anhydrase Inhibitor; Diuretic
Form:Free Base

REVIEW

 Methazolamide is carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.

REFERENCES
[1]Hassan MG, Emara KM, Mohamed HA, Abdel-Wadood HM, Ikeda R, Wada M, Kuroda N, Nakashima K (2012). Determination of memantine in rat plasma by HPLC-fluorescence method and its application to study of the pharmacokinetic interaction between memantine and methazolamide. Biomed Chromatogr. 26(2):214-9. PMID 21594878.
[2] Konstantopoulos N, Molero JC, McGee SL, Spolding B, Connor T, de Vries M, Wanyonyi S, Fahey R, Morrison S, Swinton C, Jones S, Cooper A, Garcia-Guerra L, Foletta VC, Krippner G, Andrikopoulos S, Walder KR (2012). Methazolamide is a new hepatic insulin sensitizer that lowers blood glucose in vivo. Diabetes. 61(8):2146-54. PMID 22586591.

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H302+H312+H332; H351

Precautionary Statements
P280


Current as of July 6, 2020

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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CATEGORIES

 APIs and Bioactives > Carbonic Anhydrase Inhibitors


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