5908-99-6 Atropine sulfate monohydrate AKSci J11046
 
 
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  J11046    AKSci Reference Standard
Atropine sulfate monohydrate, 99% (HPLC)
 
a-(Hydroxymethyl)benzeneacetic acid (3-endo)-8- methyl-8-azabicyclo[3.2.1]oct-3-yl ester sulfate monohydrate
IDENTITY
CAS Number:5908-99-6
MDL Number:MFCD00074815
MF:C34H46N2O6.H2SO4.H2O
MW:694.83
EINECS:200-104-8
BRN:6109275
SPECIFICATIONS & PROPERTIES
Purity:99% (HPLC)
Spectra:LCMS, FT-IR, HPLC, Polarimetry
Physical Form:White crystalline powder
Melting Point:190-193°C
Optical Rotation:-0.6 °(c=5, H2O per USP)
Long-Term Storage:Store long-term at 2-8°C
UN #:UN1544
Hazard Class:6.1; Poison
Packing Group:II

BIOLOGICAL INFO
Solubility:H2O: 2.5 g/mL; EtOH: 200 mg/mL; glycerol: 400 mg/mL (stable at 4 °C)
Application(s):Competitive muscarinic acetylcholine receptor antagonis
Form:Sulfate salt monohydrate

REVIEW
 Atropine binds to and inhibit muscarinic acetylcholine receptors, producing a wide range of anticholinergic effects.

REFERENCES
[1]Field JM, Hazinski MF, Sayre MR, et al. (November 2010). Part 1: executive summary: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation 122 (18 Suppl 3): S640-56. doi:10.1161/CIRCULATIONAHA.110.970889. PMID 20956217.
[2] Bryan E, Bledsoe; Robert S. Porter, Richard A. Cherry (2004). Ch. 3. Intermediate Emergency Care. Upper Saddle River, NJ: Pearson Prentice Hill. p. 260. ISBN 0-13-113607-0.
[3] Georgievski Z, Koklanis K, Leone J. Fixation behavior in the treatment of amblyopia using atropine. Clinical and Experimental Ophthalmology 2008; 36 (Suppl 2): A764-A765.

GHS

Pictograms

Signal Word
Danger

Hazard Statements
H300+H330

Precautionary Statements
P260; P264; P270; P271; P284; P301+P310; P304+P340; P310; P320; P330; P403+P233; P405; P501

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Current as of July 12, 2020

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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CATEGORIES
 APIs and Bioactives > Alkaloids, AChR Antagonists


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