5908-99-6 Atropine sulfate monohydrate AKSci J11046

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J11046 AKSci Reference Standard
Atropine sulfate monohydrate, 99% (HPLC)

a-(Hydroxymethyl)benzeneacetic acid (3-endo)-8- methyl-8-azabicyclo[3.2.1]oct-3-yl ester sulfate monohydrate

BIOLOGICAL INFO
Solubility:	H2O: 2.5 g/mL; EtOH: 200 mg/mL; glycerol: 400 mg/mL (stable at 4 °C)
Application(s):	Competitive muscarinic acetylcholine receptor antagonis
Form:	Sulfate salt monohydrate

REVIEW
Atropine binds to and inhibit muscarinic acetylcholine receptors, producing a wide range of anticholinergic effects.

REFERENCES

[1]	Field JM, Hazinski MF, Sayre MR, et al. (November 2010). Part 1: executive summary: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation 122 (18 Suppl 3): S640-56. doi:10.1161/CIRCULATIONAHA.110.970889. PMID 20956217.
[2]	Bryan E, Bledsoe; Robert S. Porter, Richard A. Cherry (2004). Ch. 3. Intermediate Emergency Care. Upper Saddle River, NJ: Pearson Prentice Hill. p. 260. ISBN 0-13-113607-0.
[3]	Georgievski Z, Koklanis K, Leone J. Fixation behavior in the treatment of amblyopia using atropine. Clinical and Experimental Ophthalmology 2008; 36 (Suppl 2): A764-A765.

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