480-40-0 Chrysin AKSci J10838
 
 
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  J10838    AKSci Reference Standard
Chrysin, 99% (HPLC)
 
5,7-Dihydroxyflavone
IDENTITY
CAS Number:480-40-0
MDL Number:MFCD00006834
MF:C15H10O4
MW:254.24
EINECS:207-549-7
BRN:233276
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:99% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:290-295°C
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

REVIEW
 Chrysin is a naturally occurring flavone chemically extracted from the passion flowers Passiflora caerulea and Passiflora incarnata. Honeycomb also contains small amounts. It is also reported in the mushroom Pleurotus ostreatus, chamomile, and Oroxylum indicum or Indian trumpetflower. Chrysin has been shown to induce an anti-inflammatory effect, most likely by inhibition of COX-2 expression and via IL-6 signaling.

REFERENCES
[1]Wolfman C, Viola H, Paladini A, Dajas F, Medina JH (1994). Possible anxiolytic effects of chrysin, a central benzodiazepine receptor ligand isolated from Passiflora coerulea. Pharmacol. Biochem. Behav. 47 (1): 1-4. PMID 7906886.
[2] Brown E, Hurd NS, McCall S, Ceremuga TE (2007). Evaluation of the anxiolytic effects of chrysin, a Passiflora incarnata extract, in the laboratory rat. AANA J 75 (5): 333-7. PMID 17966676.
[3] Anandhi R, Annadurai T, Anitha TS, Muralidharan AR, Najmunnisha K, Nachiappan V et al. (2012). Antihypercholesterolemic and antioxidative effects of an extract of the oyster mushroom, Pleurotus ostreatus, and its major constituent, chrysin, in Triton WR-1339-induced hypercholesterolemic rats.. J Physiol Biochem. PMID 23104078.
[4] van Meeuwen JA, Korthagen N, de Jong PC, Piersma AH, van den Berg M. (2007). (Anti)estrogenic effects of phytochemicals on human primary mammary fibroblasts, MCF-7 cells and their co-culture. Toxicol Appl Pharmacol. 221 (3): 372-83. PMID 17482226.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of April 24, 2024

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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CATEGORIES
 APIs and Bioactives > Flavonoids


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