491-80-5 Biochanin A AKSci J10812
 
 
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  J10812    AKSci Reference Standard
Biochanin A
, 99% (HPLC), powder
 
5,7-Dihydroxy-4'-methoxy-Isoflavone




IDENTITY
CAS Number:491-80-5
MDL Number:MFCD00006839
MF:C16H12O5
MW:284.26
EINECS:207-744-7
BRN:278107
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:99% (HPLC), powder
Physical Form (at 20°C):Solid
Melting Point:210-219°C
Long-Term Storage:Store long-term at -20°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Application(s):Aryl hydrocarbon receptor agonist
Form:Free Base
Research Area:Cancer

REVIEW

 Biochanin A is an O-methylated isoflavone. It is a natural organic compound in the class of phytochemicals known as flavonoids. Biochanin A can be found in red clover in soy, in alfalfa sprouts, in peanuts, in chickpea (Cicer arietinum) and in other legumes. Biochanin A is classified as a phytoestrogen, acting as an agonist of the Aryl hydrocarbon receptor and has putative benefits in dietary cancer prophylaxis It has also been found to inhibit fatty acid amide hydrolase.

REFERENCES
[1]Beck V, Rohr U, Jungbauer A. Phytoestrogens derived from red clover: an alternative to estrogen replacement therapy? J Steroid Biochem Mol Biol. 2005 Apr;94(5):499-518.
[2] Moon YJ, Wang X, Morris ME Dietary flavonoids: effects on xenobiotic and carcinogen metabolism. Toxicol In Vitro. 2006 Mar;20(2):187-210.
[3] Booth NL, Piersen CE, Banuvar S, Geller SE, Shulman LP, Farnsworth NR. Clinical studies of red clover (Trifolium pratense) dietary supplements in menopause: a literature review. Menopause. 2006 Mar-Apr;13(2):251-64.
[4] Medjakovic S, Jungbauer A. Red clover isoflavones biochanin A and formononetin are potent ligands of the human aryl hydrocarbon receptor. J Steroid Biochem Mol Biol. 2008 Jan;108(1-2):171-7.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of December 6, 2022

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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