REVIEW Malotilate is an antifibrotic and hepatotropic agent, used in the treatment of liver disease. It can activate the liver, inhibit the progress of liver fibrosis. Malotilate is also applicable to chronic hepatitis and cirrhosis.
REFERENCES
[1]
Ryle, Peter R.; Dumont, J. M. Malotilate: the new hope for a clinically effective agent for the treatment of liver disease. Alcohol and Alcoholism (Oxford, United Kingdom). (1987) 22(2): 121-41.
[2]
Mathurin, Philippe; Poynard, Thierry. Pharmacological treatment for alcoholic hepatitis and cirrhosis: present practice and future strategies. Edited by Sherman, David I. N.; Preedy, Victor R.; Watson, Ronald Ross. Ethanol and the Liver. (2002) 592-613.
[3]
Itakura M; Tsuchiya M; Yamashita K; Oda T. Malotilate (diisopropyl 1,3-dithiol-2-ylidenemalonate) increases liver de novo purine synthesis and amidophosphoribosyltransferase activity. The Journal of Pharmacology and Experimental Therapeutics. (1986) 237(3): 794-8.
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