59937-28-9 Malotilate AKSci J10783
 
 
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  J10783    AKSci Reference Standard
Malotilate, >98% (HPLC)
 



IDENTITY
CAS Number:59937-28-9
MDL Number:MFCD00867646
MF:C12H16O4S2
MW:288.38
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:>98% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:60-65°C
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

REVIEW
 Malotilate is an antifibrotic and hepatotropic agent, used in the treatment of liver disease. It can activate the liver, inhibit the progress of liver fibrosis. Malotilate is also applicable to chronic hepatitis and cirrhosis.

REFERENCES
[1]Ryle, Peter R.; Dumont, J. M. Malotilate: the new hope for a clinically effective agent for the treatment of liver disease. Alcohol and Alcoholism (Oxford, United Kingdom). (1987) 22(2): 121-41.
[2] Mathurin, Philippe; Poynard, Thierry. Pharmacological treatment for alcoholic hepatitis and cirrhosis: present practice and future strategies. Edited by Sherman, David I. N.; Preedy, Victor R.; Watson, Ronald Ross. Ethanol and the Liver. (2002) 592-613.
[3] Itakura M; Tsuchiya M; Yamashita K; Oda T. Malotilate (diisopropyl 1,3-dithiol-2-ylidenemalonate) increases liver de novo purine synthesis and amidophosphoribosyltransferase activity. The Journal of Pharmacology and Experimental Therapeutics. (1986) 237(3): 794-8.
[4] Taninaka, Kuniaki; Hirano, Akira; Kurono, Hitoshi Fungicidal 1,3-dithiol-2-ylidenemalonic acid esters Ger. Offen. (1976), DE 2545569 A1 19760429.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of April 25, 2024

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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