83915-83-7, 76547-98-3 Lisinopril dihydrate AKSci J10628
 
 
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  J10628    AKSci Reference Standard
Lisinopril dihydrate
, >98% (HPLC)
 
(S)-1-[N2-(1-carboxy-3-phenylpropyl)-lysyl-proline dihydrate
MK-521




IDENTITY
CAS Number:83915-83-7, 76547-98-3
MDL Number:MFCD01698825
MF:C21H31N3O5.2H2O
MW:441.52
EINECS:278-488-1
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:>98% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:172-176°C
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:Soluble in water (>10mg/mL) or DMSO (6.5mg/mL)

REVIEW

 Lisinopril was the third ACE inhibitor (after captopril and enalapril) and was introduced into therapy in the early 1990s. A number of properties distinguish it from other ACE inhibitors: It is hydrophilic, has a long half-life and tissue penetration, and is not metabolized by the liver. Lisinopril is the lysine-analog of enalapril. Unlike other ACE inhibitors, it is not a prodrug and is excreted unchanged in the urine.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of September 29, 2022

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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CATEGORIES

 APIs and Bioactives > ACE Inhibitors


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