REVIEW Procainamide is sodium channel blocker. It stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses thereby effecting local anesthetic action. Procainamide's major active metabolite is N-acetylprocainamide, which is approximately equipotent with the parent drug as an antiarrhythmic agent.
REFERENCES
[1]
Najer, Henry; Joannic, Michel Preparation of mono- and dihydrochloride of 2-diethylaminoethylamide and of 3-diethylaminopropylamide of p-aminobenzoic acid Annales Pharmaceutiques Francaises (1955), 13, 556-9.
[2]
Nakajima, Isao; Tsujikawa, Kouji; Kato, Yukuru; Shinuchi, Tadami 4-Amino-N-(diethylaminoethyl)benzamides Ger. Offen. (1972), DE 2162917 A 19720907.
[3]
Zamponi GW, Sui X, Codding PW, French RJ. Dual actions of procainamide on batrachotoxin-activated sodium channels: open channel block and prevention of inactivation. Biophys J. 1993 Dec;65(6):2324-34.
[4]
Fenster PE, Comess KA, Marsh R, Katzenberg C, Hager WD. Conversion of atrial fibrillation to sinus rhythm by acute intravenous procainamide infusion. Am Heart J. 1983 Sep;106(3):501-4.
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