520-34-3 Diosmetin AKSci J10577
 
 
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  J10577    AKSci Reference Standard
Diosmetin, >98% (HPLC), powder
 



IDENTITY
CAS Number:520-34-3
MDL Number:MFCD00017425
MF:C16H12O6
MW:300.26
EINECS:208-291-8
BRN:294492
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:>98% (HPLC), powder
Physical Form (at 20°C):Solid
Melting Point:257-259°C
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO 60mg/ml; Water <1mg/ml; Ethanol 17mg/ml
Application(s):Diosmetin is a bioflavonoid found in spearmint, oregano, and many other plants
Form:Free Base
Research Area:Cancer

REVIEW
 Diosmetin is a natural flavonoid that impedes human CYP1A enzyme activity. Diosmetin has anti-mutagenic and anti-allergic characteristic. IC50 data: CYP1B1: IC50 = 29 nM (human); ABCC1: IC50 = 140 nM (human); CYP1A2: IC50 = 2.44 µM (human); MRP1: IC50 = 3 µM (human); MRP2: IC50 >50 µM (human); CYP1B1; Ki data: Ki= 16 nM (human); ABCC1: Ki= 89 nM (human).

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H302

Precautionary Statements
P264; P270; P301+P312; P330; P501

Current as of April 20, 2024

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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CATEGORIES
 APIs and Bioactives > Flavonoids


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