REVIEW An immunosuppressant drug used to prevent rejection in organ transplantation. It inhibits inosine monophosphate dehydrogenase, the enzyme that controls the rate of synthesis of guanine monophosphate in the de novo pathway of purine synthesis used in the proliferation of B and T lymphocytes.
REFERENCES
[1]
Clayton PA, McDonald SP, Chapman JR, Chadban SJ (2012). Mycophenolate versus azathioprine for kidney transplantation: a 15-year follow-up of a randomized trial. Transplantation. 94(2):152-8. PMID 22728292.
[2]
Wiesen MH, Farowski F, Feldk?tter M, Hoppe B, M?ller C (2012). Liquid chromatography-tandem mass spectrometry method for the quantification of mycophenolic acid and its phenolic glucuronide in saliva and plasma using a standardized saliva collection device. J Chromatogr A. 1241:52-9. PMID 22552204.
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