24280-93-1 Mycophenolic acid AKSci J10564
 
 
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  J10564    AKSci Reference Standard
Mycophenolic acid
, 99% (HPLC)
 



IDENTITY
CAS Number:24280-93-1
MDL Number:MFCD00036814
MF:C17H20O6
MW:320.34
EINECS:246-119-3
BRN:1295848
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:99% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:139-146°C
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: 64mg/mL; H2O: <1mg/mL; EtOH: 18mg/mL
Application(s):Antibiotic; Inosine monophosphate dehydrogenase inhibitor
Form:Free Base

REVIEW

 An immunosuppressant drug used to prevent rejection in organ transplantation. It inhibits inosine monophosphate dehydrogenase, the enzyme that controls the rate of synthesis of guanine monophosphate in the de novo pathway of purine synthesis used in the proliferation of B and T lymphocytes.

REFERENCES
[1]Clayton PA, McDonald SP, Chapman JR, Chadban SJ (2012). Mycophenolate versus azathioprine for kidney transplantation: a 15-year follow-up of a randomized trial. Transplantation. 94(2):152-8. PMID 22728292.
[2] Wiesen MH, Farowski F, Feldk?tter M, Hoppe B, M?ller C (2012). Liquid chromatography-tandem mass spectrometry method for the quantification of mycophenolic acid and its phenolic glucuronide in saliva and plasma using a standardized saliva collection device. J Chromatogr A. 1241:52-9. PMID 22552204.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Danger

Hazard Statements
H302; H341; H360; H372; H410

Precautionary Statements
P201; P202; P260; P264; P270; P273; P281; P301+P312; P308+P313; P330; P391; P405; P501


Current as of September 29, 2022

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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CATEGORIES

 APIs and Bioactives > Immunomodulators


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