38194-50-2 Sulindac AKSci J10535
 
 
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  J10535    AKSci Reference Standard
Sulindac, >99% (HPLC), powder
 
(Z)-2-(3-(4-(methylsulfinyl)benzylidene)-6-fluoro-2-methyl-3H-inden-1-yl)acetic acid
IDENTITY
CAS Number:38194-50-2
MDL Number:MFCD00599589
MF:C20H17FO3S
MW:356.41
EINECS:253-819-2
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:>99% (HPLC), powder
Physical Form (at 20°C):Solid
Melting Point:182-189°C
Long-Term Storage:Store long-term at -20°C
DOT/IATA TRANSPORT INFORMATION
UN #:UN2811
Hazard Class:6.1; Poison
Packing Group:III
A hazmat fee may apply to certain package sizes and shipment methods. Please check pricing table for an indicator of applicable hazmat fees.

BIOLOGICAL INFO
Solubility:MeOH: 50mg/mL
Application(s):COX-1 inhibitor
Form:Free Base

REVIEW
 An non-steroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase COX-1.

REFERENCES
[1]Whitt JD, Li N, Tinsley HN, Chen X, Zhang W, Li Y, Gary BD, Keeton AB, Xi Y, Abadi AH, Grizzle WE, Piazza GA (2012). A novel sulindac derivative that potently suppresses colon tumor cell growth by inhibiting cGMP phosphodiesterase and β-catenin transcriptional activity. Cancer Prev Res (Phila). 5(6):822-33. PMID 22556201.
[2] Zou W, Roth RA, Younis HS, Malle E, Ganey PE (2011). Neutrophil-cytokine interactions in a rat model of sulindac-induced idiosyncratic liver injury. Toxicology. 290(2-3):278-85. PMID 22019926.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Danger

Hazard Statements
H301; H317; H334; H361

Precautionary Statements
P201; P202; P261; P264; P270; P272; P280; P301+P310; P302+P352; P304+P341; P308+P313; P321; P330; P333+P313; P363; P405; P501

Current as of September 8, 2025

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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All products are stocked and shipped from the SF Bay, California, USA via FedEx, UPS or DHL.
All batches backed with full quality assurance.
⚠️
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.
⚠️

WARNING: Attention California residents: This product can expose you to chemicals including Sulindac, which is known to the State of California to cause birth defects or other reproductive harm. For more information, go to www.P65Warnings.ca.gov.




CATEGORIES
 APIs and Bioactives > NSAIDs


PubChem