5633-20-5 Oxybutynin AKSci J10527
 
 
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  J10527    
Oxybutynin
, 98% (HPLC)
 
Ditropan
Lyrinel XL
Oxytrol




IDENTITY
CAS Number:5633-20-5
MDL Number:MFCD00865252
MF:C22H31NO3
MW:357.49
SPECIFICATIONS & PROPERTIES
Purity:98% (HPLC)
Spectra:NMR, LCMS, FT-IR, HPLC
Physical Form:White powder
Melting Point:57-61°C
Long-Term Storage:Store at room temperature

BIOLOGICAL INFO
Solubility:DMSO: 72mg/mL; H2O: <1mg/mL; EtOH: 72mg/mL
Application(s):Muscarinic Antagonist
Form:Free Base

REVIEW

 Oxybutynin exerts a direct antispasmodic effect on smooth muscle and inhibits the muscarinic action of acetylcholine on smooth muscle. No blocking effects occur at skeletal neuromuscular junctions or autonomic ganglia (antinicotinic effects). By inhibiting particularily the M1 and M2 receptors of the bladder, detrusor activity is markedly decreased.

REFERENCES
[1]Tupker RA, Harmsze AM, Deneer VH: Oxybutynin therapy for generalized hyperhidrosis. Arch Dermatol. 2006 Aug;142(8):1065-6.
[2] Mijnhout GS, Kloosterman H, Simsek S, Strack van Schijndel RJ, Netelenbos JC: Oxybutynin: dry days for patients with hyperhidrosis. Neth J Med. 2006 Oct;64(9):326-8.
[3] Schollhammer M, Misery L: Treatment of hyperhidrosis with oxybutynin. Arch Dermatol. 2007 Apr;143(4):544-5.

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of January 18, 2019


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CATEGORIES

 APIs and Bioactives > AChR Antagonists


PubChem